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Original Research
Zohreh Ebrahimnezhad, Nosratollah Zarghami*, Manoutchehr Keyhani, Soumaye Amirsaadat, Abolfazl Akbarzadeh, Mohammad Rahmati, Zohreh Mohammad Taheri, Kazem Nejati-Koshki
Bioimpacts. 2013;3(2): 67-74. doi: 10.5681/bi.2013.005
PMCID: PMC3713872     PMID: 23878789     Scopus ID: 84881534495    
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Original Research
Umamaheswaran Gurusamy*, Steven Aibor Dkhar, Arun Kumar Annan Sudarsan, Katiboina Srinivasa Rao, Dharanipragada Kadambari, Chandrasekaran Adithan
Bioimpacts. 2014;4(2): 95-100. doi: 10.5681/bi.2014.016
PMCID: PMC4097978     PMID: 25035853     Scopus ID: 84905440942    
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Original Research
Babak Nami* ORCID, Armin Ghasemi-Dizgah, Akbar Vaseghi
Bioimpacts. 2016;6(2): 105-110. doi: 10.15171/bi.2016.15
PMCID: PMC4981248     PMID: 27525228     Scopus ID: 84983485978    
Original Research
Mohammad-Hossein Biglu*, Parvaneh Abotalebi, Mostafa Ghavami*
Bioimpacts. 2016;6(4): 211-217. doi: 10.15171/bi.2016.28
PMCID: PMC5326669     PMID: 28265537     Scopus ID: 85013028944    
Original Research
Muhammad Nuh Musa, Sheba Rani David* ORCID, Ihsan Nazurah Zulkipli ORCID, Abdul Hanif Mahadi, Srikumar Chakravarthi, Rajan Rajabalaya* ORCID
Bioimpacts. 2017;7(4): 227-239. doi: 10.15171/bi.2017.27
PMCID: PMC5801534     PMID: 29435430     Scopus ID: 85040995353    
Original Research
Hassan Moghtaderi, Houri Sepehri*, Ladan Delphi, Farnoosh Attari
Bioimpacts. 2018;8(3): 185-194. doi: 10.15171/bi.2018.21
PMCID: PMC6128975     PMID: 30211078     Scopus ID: 85050670106    
Original Research
Ayuob Aghanejad, Hiwa Babamiri, Khosro Adibkia, Jaleh Barar ORCID, Yadollah Omidi* ORCID
Bioimpacts. 2018;8(2): 117-127. doi: 10.15171/bi.2018.14
PMCID: PMC6026525     PMID: 29977833     Scopus ID: 85048082430    
Original Research
Sepideh Parvizpour, Jafar Razmara, Mohammad M. Pourseif, Yadollah Omidi* ORCID
Bioimpacts. 2019;9(1): 45-56. doi: 10.15171/bi.2019.06
PMCID: PMC6378095     PMID: 30788259     Scopus ID: 85060470196    
Using immunoinformatic tools, a multi-epitope peptide vaccine (consisting of CD8+cytotoxic T lymphocytes epitopes, helper epitopes and adjuvant) was designed to combat the triple-negative breast cancer. The vaccine showed acceptable immunogenicity and potential to stimulate both cellular and humoral immune responses.
Original Research
Mohammad Reza Asgharzadeh, Mohammad M. Pourseif, Jaleh Barar ORCID, Morteza Eskandani, Mojtaba Jafari Niya, Mohammad Reza Mashayekhi, Yadollah Omidi* ORCID
Bioimpacts. 2019;9(3): 145-159. doi: 10.15171/bi.2019.19
PMCID: PMC6726749     PMID: 31508330     Scopus ID: 85071154393    
Increased expression of TSGA10 associated with the reduced metastasis in the MDA-MB-231 cells. TSGA10 showed interaction with HIF-1α with high affinity. TSGA10 expression is altered under the hypoxia, indicating its potential as a bio-target for cancer therapy.
Original Research
Fatemeh Abedi Jafari ORCID, Asghar Abdoli* ORCID, Reza Pilehchian, Neda Soleimani, Seyed Masoud Hosseini
BioImpacts. 2022;12(5): 405-414. doi: 10.34172/bi.2021.25
PMCID: PMC9596882     PMID: 36381634     Scopus ID: 85140264436    
The experiment concluded that the C. novyi nontoxic might be a suitable and safe candidate, a novel therapeutic approach to encounter such hypoxic regions in the center of tumors
Original Research
Amir Shakouri ORCID, Houman Kahroba, Hamed Hamishekar, Jalal Abdolalizadeh* ORCID
BioImpacts. 2022;12(2): 115-126. doi: 10.34172/bi.2021.39
PMCID: PMC8905592     PMID: 35411300     Scopus ID: 85126459418    
In the first stage of the procedure, medical leech saliva was extracted and for encapsulating these proteins, liposome technique was applied. Continually, nano drug applied on cancer cells and expression of genes were evaluated by Real- Time PCR and western blotting.
Original Research
Javad Firouzi ORCID, Fattah Sotoodehnejadnematalahi, Alireza Shokouhifar ORCID, Mahsa Rahimi, Niloufar Sodeifi, Parisa Sahranavardfar, Masoumeh Azimi, Ehsan Janzamin, Majid Safa, Marzieh Ebrahimi* ORCID
BioImpacts. 2022;12(5): 415-429. doi: 10.34172/bi.2022.23336
PMCID: PMC9596878     PMID: 36381630     Scopus ID: 85140213651    
The effect of silibinin evaluated on self-renewal, tumorgenicity, and metastasis potential of Mammospheres derived from MCF-7, MDA-MB231 cell lines, and MDA-MB468 aggregated cells
Original Research
Laura Cabeza ORCID, Mazen M. El-Hammadi ORCID, Raul Ortiz ORCID, Maria D. Cayero-Otero, Julia Jiménez-López ORCID, Gloria Perazzoli ORCID, Lucia Martin-Banderas ORCID, Jose M. Baeyens ORCID, Consolación Melguizo* ORCID, Jose Prados ORCID
BioImpacts. 2022;12(6): 515-531. doi: 10.34172/bi.2022.23433
PMCID: PMC9809141     PMID: 36644541     Scopus ID: 85140308481    
These results suggest that our PTX-PLGA NPs could be a suitable strategy for breast cancer therapy, improving antitumor drug efficiency and reducing systemic toxicity without altering its mechanism of action.
Original Research
Nasrollah Jabbari ORCID, Maryam Feghhi, Omid Esnaashari, Hamid Soraya, Jafar Rezaie* ORCID
BioImpacts. 2022;12(6): 549-559. doi: 10.34172/bi.2022.23489
PMCID: PMC9809134     PMID: 36644548     Scopus ID: 85143387474    
Treatment of MCF-10a, MCF-7, and MDA-MD-231 cells with Gallic acid resulted in inhibition in the activity of the exosomal secretory pathway. Gallic acid can decrease the expression of genes involved in exosomes biogenesis (Alix and CD63) and secretion (Rab proteins). In addition, Gallic acid can change the expression of autophagy markers (LC3 and P62) in these cells. MVB: multivesicular body.
Original Article
Raghdah S. Bawadud ORCID, Mayson H. Alkhatib* ORCID
Bioimpacts. 2023;13(2): 145-157. doi: 10.34172/bi.2023.23515
PMCID: PMC10182446     PMID: 37193079     Scopus ID: 85152114664    
Co-delivery of NE-DTX+TQ may probably inhibit the proliferation of T47D via the induction of apoptosis and autophagy pathways and impede the migration by reducing the BCSC population and downregulating TWIST-1 expression to decrease the epithelial-to-mesenchymal transition (EMT) of breast cancer cells
Original Research
Behnaz Babaye Abdollahi ORCID, Marjan Ghorbani, Hamed Hamishehkar, Reza Malekzadeh, Alireza Farajollahi* ORCID
Bioimpacts. 2023;13(1): 17-29. doi: 10.34172/bi.2022.23682
PMCID: PMC9923814     PMID: 36816996     Scopus ID: 85152117585    
This study shows the positive effect of synthesized Trastuzumab loaded PEG-Fe3O4@Au nanoparticleson increasing the death rate of Breast cancer cells during megavoltage radiation therapy.
Original Article
Yuri Yu. Shchegolev ORCID, Danila V. Sorokin, Alexander M. Scherbakov* ORCID, Olga E. Andreeva ORCID, Diana I. Salnikova ORCID, Ekaterina I. Mikhaevich ORCID, Margarita V. Gudkova ORCID, Mikhail A. Krasil’nikov ORCID
Bioimpacts. 2023;13(4): 313-321. doi: 10.34172/bi.2023.27490
PMCID: PMC10460766     PMID: 37645026     Scopus ID: 85168127787    
Prolonged cell treatment with mTOR inhibitor rapamycin leads to the development of resistance. Exosomes of resistant cells induce the resistance to rapamycin in the parent MCF-7cells. Exosome-induced resistance reproduces the changes revealed in the rapamycin-resistant cells, including the activation of ERK/AP-1.
Original Article
Nazila Jalilzadeh ORCID, Neda Barzgar Barough, Mehrdad Karami, Amir Baghbanzadeh, Kobra Velaei* ORCID
Bioimpacts. 2024;14(3): 27591. doi: 10.34172/bi.2023.27591
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Zeinab Mazloumi ORCID, Ali Rafat, Khadijeh Dizaji Asl, Mohammad Karimipour, Dariush Shanehbandi, Mehdi Talebi, Majid Montazer, Ali Akbar Movassaghpour, Alireza Dehnad, Raheleh Farahzadi, Hojjatollah Nozad Charoudeh* ORCID
Bioimpacts. 2024;14(4): 27640. doi: 10.34172/bi.2023.27640
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Original Article
Zahra Alidoost ORCID, Farnoosh Attari* ORCID, Fatemeh Saadatpour, Ehsan Arefian
Bioimpacts. 2024;14(1): 27758. doi: 10.34172/bi.2023.27758
PMCID: PMC10844590     PMID: 38327636    
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Original Article
Snehal Aditya Arvindekar* ORCID, Sanket Rathod ORCID, Prafulla Balkrishna Choudhari ORCID, Pradnya Kiran Mane ORCID, Aditya Umesh Arvindekar* ORCID, Suraj Narayan Mali ORCID, Bapu Thorat ORCID
Bioimpacts. 2024;. doi: 10.34172/bi.2024.27783
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Original Article
Hamed Zare ORCID, Hamid Bakherad* ORCID, Arman Nasr Esfahani, Mohamad Norouzi, Hossein Aghamollaei, Seyed Latif Mousavi Gargari, Fatemeh Mahmoodi, Mahdi Aliomrani, Walead Ebrahimizadeh
Bioimpacts. 2024;14(2): 27829. doi: 10.34172/bi.2023.27829
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