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Mohammad Amir Amirkhani, Rashin Mohseni, Masoud Soleimani, Alireza Shoae-Hassani, Mohammad Ali Nilforoushzadeh*
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Fahsai Kantawong*, Chanidapa Saksiriwisitkul, Chanakan Riyapa, Suchalinee Limpakdee, Phenphichar Wanachantararak, Thasaneeya Kuboki
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Mohammad A. Rafi*, Abass Alavi*
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Navid Hosseini Mansoub*, Mehmet Gürdal, Elif Karadadaş, Hilal Kabadayi, Seda Vatansever, Gulinnaz Ercan
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Stephan Born*, Max Johannes Dörfel, Philip Hartjen, Seyed Ali Haschemi Yekani, Julia Luecke, Juliane Katharina Meutsch, Julie Katharina Westphal, Moritz Birkelbach, Robert Köhnke, Ralf Smeets, Michael Krueger
The purification process for stromal vascular fraction (SVF) can be performed using additional short plastic adherence incubation step (16-20h). This process leads in 24h to a predictable GMP-compliant cell-product. This product is more homogenous than the SVF.
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Fatemeh Rahimi-Sherbaf  , Samad Nadri , Ali Rahmani, Atousa Dabiri Oskoei*
Stem cells has shown different behavior and differentiation pattern due to its microenvironment. The neural differentiation of PMSCs were affected by its substrate. 3D hybrid nanoscaffold has different impact on neural differentiation of PMSCs
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Sevda Rahimzadeh , Reza Rahbarghazi, Somayeh Aslani, Hadi Rajabi, Zeinab Latifi, Majid Farshdousti Hagh, Alireza Nourazarian, Hojjatollah Nozad Charoudeh, Mohammad Nouri* , Alireza Abhari*
Adipose-derived mesenchymal stem cells were incubated with osteogenic differentiation medium. RNA and DNA were extracted on days 0, 7, 14 and 21 days of differentiation period. The expression and promoter methylation of DLX3, ATF4, and FRA1 genes were analyzed by real-time polymerase chain reaction and methylation-specific quantitative PCR, respectively
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Roya Hesari , Mina Keshvarinia, Mahboubeh Kabiri, Iman Rad , Kazem Parivar, Hoorieh Hoseinpoor, Rezvan Tavakoli, Masoud Soleimani, Fatemeh Kouhkan , Soheila Zamanluee, Hana Hanaee-Ahvaz*
PRP induces in vitro chondrogenesis, as well as TGF-β with lesser inflammatory and hypertrophic side effects.
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Zeinab Karimi , Sahar Janfeshan, Elias Kargar Abarghouei, Seyedeh-Sara Hashemi*
Renal functional and structural disturbance induced by renal bilateral ischemia/reperfusion. However, administration of bone marrow stem cell (1.5×106 cells, i.p., per rat) improved renal function and appearance. Protective effect of BMSCs related to modulation of mRNA expression of TLR2 and TLR4.
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Zeinab Ghaffarinovin , Omid Soltaninia, Yousef Mortazavi, Abdolreza Esmaeilzadeh, Samad Nadri*
The simultaneous application of fibrous scaffold + AF-MSCs + PRP has positive effects on bone regeneration.
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Nadezhda V. Maksimova , Anna V. Michenko, Olga A. Krasilnikova , Ilya D. Klabukov* , Igor Yu. Gadaev , Michael E. Krasheninnikov , Pavel A. Belkov, Aleksey V. Lyundup
Three-year follow-up of patients, treated for diabetic foot ulcers with mesenchymal stromal cells that revealed absence of ulcer recurrence, neoplasms, and scar contracture. Collagen ultrasound density decreased by 57% and the epidermal thickness increased by 72% in the area of healed ulcers.
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Solmaz Zakhireh , Jaleh Barar* , Younes Beygi-Khosrowshahi, Abolfazl Barzegari, Yadollah Omidi, Khosro Adibkia*
The pollen grain of Pistacia vera L. is proposed as a scaffolding building block with the encapsulation capability of bioactive compounds. A modified simple method was developed to create nonallergic hollow pollen grains (HPGs).
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Javad Firouzi , Fattah Sotoodehnejadnematalahi, Alireza Shokouhifar , Mahsa Rahimi, Niloufar Sodeifi, Parisa Sahranavardfar, Masoumeh Azimi, Ehsan Janzamin, Majid Safa, Marzieh Ebrahimi*
The effect of silibinin evaluated on self-renewal, tumorgenicity, and metastasis potential of Mammospheres derived from MCF-7, MDA-MB231 cell lines, and MDA-MB468 aggregated cells
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Laura Cabeza , Mazen M. El-Hammadi , Raul Ortiz , Maria D. Cayero-Otero, Julia Jiménez-López , Gloria Perazzoli , Lucia Martin-Banderas , Jose M. Baeyens , Consolación Melguizo* , Jose Prados
These results suggest that our PTX-PLGA NPs could be a suitable strategy for breast cancer therapy, improving antitumor drug efficiency and reducing systemic toxicity without altering its mechanism of action.
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Raghdah S. Bawadud , Mayson H. Alkhatib*
Co-delivery of NE-DTX+TQ may probably inhibit the proliferation of T47D via the induction of apoptosis and autophagy pathways and impede the migration by reducing the BCSC population and downregulating TWIST-1 expression to decrease the epithelial-to-mesenchymal transition (EMT) of breast cancer cells
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Maryam Sadat Khoramgah , Hossein Ghanbarian, Javad Ranjbari, Nilufar Ebrahimi, Fatemeh Sadat Tabatabaei Mirakabad, Navid Ahmady Roozbahany, Hojjat Allah Abbaszadeh* , Simzar Hosseinzadeh*
PTFE/PVA/GO/ADSCs construct has a promising result in in-vivo bone regeneration and could be used for large animal models and subsequently for clinical usage.
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Ali KarbalaeiMahdi , Kaykhosro Moridi , Marzieh Ghollasi*
PCL-PANI-GEL fibers showed to be capable candidates for cell attachment and growth. Furthermore, they proved to be of excellent use in bone tissue differentiation.
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Zahra Olfat Noubari , Asal Golchin, Marziyeh Fathi* , Ailar Nakhlband*
The prepared CS-based hydrogels with desired properties including porous structure, high swelling ability, and cytocompatibility did not show oxidative stress for the nesting of stem cells.
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Mohammad Samiei , Elaheh Dalir Abdollahinia , Nazanin Amiryaghoubi , Marziyeh Fathi* , Jaleh Barar , Yadollah Omidi*
Injectable thermosensitive hydrogel (PNIPAAm-g-CS copolymer/gelatin hybrid hydrogel) can be used for osteogenic differentiation of human dental pulp stem cells (hDPSCs).
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Mohammadreza Dastouri* , Hilal Ozdag , Ahmet Ruchan Akar , Alp Can
In this study, we demonstrate a multi-step differential differentiation of iPS cells into EPCs and VSMCs, unlike previous studies in which iPS cells have been induced to differentiate into ECs. Concomitantly, during the differentiation protocol, Myc and Klf4 oncogene expressions were also analyzed from a translational perspective.
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Behnaz Ahrabi , Hojjat Allah Abbaszadeh* , Abbas Piryaei, Faezeh Shekari, Navid Ahmady Roozbahany, Mahya Rouhollahi, Forough Azam Sayahpour, Mahnaz Ahrabi, Hadi Azimi, Reza Moghadasali*
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Fatemeh Ganji , Marzieh Ebrahimi, Ali Shirani, Mahtab Golmohammadi, Mazaher Gholipourmalekabadi, Maryam Kashanian, Kiana Koolaeinezhad, Hamid Reza Davari, Seyed Ali Javad Mousavi, Hamid Reza Aghayan, Babak Arjmand, Ramin Heshmat, Nushin Karkuki Osguei, Ali Samadikuchaksaraei*
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Duong Thi Thuy Le* , Cuong Manh Vu , Thuy Thi Bich Ly, Nam Trung Nguyen, Phuong Thi Mai Nguyen, Ha Hoang Chu
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Nahideh Nazdikbin Yamchi , Farhad Amjadi, Rahim Beheshti, Mehdi Hassanpour, Reza Shirazi, Amin Tamadon , Reza Rahbarghazi , Mahdi Mahdipour*
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Azin Shahmohammadi , Hadi Samadian, Saeed Heidari Keshel, Khodabakhsh Rashidi, Amir Kiani, Masoud Soleimani*, Farjam Goudarzi*
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