Ghaith Aljayyoussi, Muthanna Abdulkarim, Peter Griffiths, Mark Gumbleton*
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Syed Baker, Devaraju Rakshith, Kumara Shanthamma Kavitha, Parthasarathy Santosh, Holalu Umapathy Kavitha, Yashavantha Rao, Sreedharamurthy Satish*
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Mohammad Babaei, Maryam Ganjalikhani*
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Samira Jafari, Solmaz Maleki Dizaj, Khosro Adibkia*
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Maryam Khalkhali, Somayeh Sadighian, Kobra Rostamizadeh*, Farhad Khoeini, Mehran Naghibi, Nahid Bayat, Mina Habibizadeh, Mehrdad Hamidi
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Morteza Mahmoudi, Mingming Zhao, Yuka Matsuura, Sophie Laurent, Phillip C. Yang, Daniel Bernstein, Pilar Ruiz-Lozano*, Vahid Serpooshan*
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Inna Garmasheva*, Nadezhda Kovalenko, Sergey Voychuk, Andriy Ostapchuk, Olena Livins’ka, Ljubov Oleschenko
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Saeideh Same, Ayuob Aghanejad, Sattar Akbari Nakhjavani, Jaleh Barar  , Yadollah Omidi*
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Mahdi Mohseniazar, Mohsen Barin, Habib Zarredar, Siamak Alizadeh, Dariush Shanehbandi*
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Mohsen Ebrahimi, Mohammad Johari-Ahar, Hossein Hamzeiy*, Jaleh Barar , Omid Mashinchian, Yadollah Omidi*
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Mojtaba Taran, Maryam Rad, Mehran Alavi*
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Mostafa Akbarzadeh Khiavi , Azam Safary , Jaleh Barar , Hamed Farzi-Khajeh, Abolfazl Barzegari, Rahimeh Mousavi, Mohammad Hossein Somi* , Yadollah Omidi*
The current study introduces an efficient ROS-responsive enzyme-based nanobiosystem and its biological impact in colon cancer therapy. Based on physicochemical properties, AuNPs-PEG-RNase A effectively induced apoptosis in SW-480 colon cancer cells and resulted in a significant reduction in cancer cell viability.
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Maryam Asariha , Azam Chahrdoli, Farshad Qalekhani, Mahnaz Ghowsi, Mehdi Fouladi, Maryam Gholamhosseinpour, Ali Fattahi*
In this study biocompatible gold nanoparticles (GNPs) were synthesized using chondroitin sulfate (CHS) as reducing and capping materials. CHS-GNPs were characterized (UV, XRD-FTIR and TEM) and their biological (antibacterial, antioxidant and cytotoxicity effects and blood compatibility) and electrochemical properties were evaluated.
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Shahram Parvaneh , Fatemeh Khademi, Gisya Abdi, Abdolhamid Alizadeh, Ali Mostafaie*
We could fabricate stable and high active Fe3O4@SiO2/NH2, and antibodies were conjugated to the surface of them from the Fc region, causing a higher binding capacity with no alteration or inhibition in the paratope area of the antibody molecule.
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Ranjita Misra* , Bamadeb Patra, Sudha Varadharaj, Rama Shanker Verma*
Formulation of siRNA adsorbed drug loaded cationic PLGA NPs. Treatment of cells with siRNA adsorbed drug loaded cationic NPs leads to endosomal escape of drugs and siRNA, thereby increasing the efficiency of the therapeutic components inducing more cytotoxicity.
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Soheila Rostami , Farzaneh Tafvizi* , Hamid Reza Kheiri Manjili
The findings suggest that F-Lys-TMX NPs are more effective and have the potential for cell proliferation inhibition and apoptosis induction compared to the TMX. Hence, F-Lys-TMX NPs can be considered as an anti-cancer agent against MCF-7 breast cancer cells.
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Vahid Ghafouri* , Majid Badieirostami, Morteza Fathipour
Schematic of the microfluidic device, top view and cross section of the middle part of the microfluidic device, tumor cell labeled with the functionalized antibodies with the Fe3O4 PMNPs, surface functionalization of the Si nanowires, SEM images of the middle part of the Si substrate with well-aligned SiNWs, SEM images of the tilted view of cancer cells trapped on the nanowires substrate microfluidic channel.
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Zhengmin Liang , Miaoxuan Li, Jiamin Ni, Tariq Hussain, Jiao Yao, Yinjuan Song, Yiduo Liu, Haoran Wang, Xiangmei Zhou*
CFP10-NPs significantly enhanced the secretion of TNF-α and IL-1β in J774A.1 macrophages. Mucosal immunization with CFP10-NPs significantly increased the levels of TNF-α, IL-1β, IgA and CFP10-specific IFN-γ, and decreased bacterial load in lungs and spleen of M. bovis-infected mice.
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Behnaz Babaye Abdollahi , Marjan Ghorbani, Hamed Hamishehkar, Reza Malekzadeh, Alireza Farajollahi*
This study shows the positive effect of synthesized Trastuzumab loaded PEG-Fe3O4@Au nanoparticleson increasing the death rate of Breast cancer cells during megavoltage radiation therapy.
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Tina Sepasi , Farhad Bani, Reza Rahbarghazi, Abbas Ebrahimi-Kalan, Mohammad-Reza Sadeghi, Seyedeh Zahra Alamolhoda, Amir Zarebkohan* , Tahereh Ghadiri, Huile Gao
Efficient gene delivery to the brain using CDX-modified chitosan nanoparticles. Given the vital effects ofcargo's physicochemical features on the targeting ability of functionalized nanoparticles, we successfullyevaluated the brain accumulation of the mentioned nanocomplexes and their distribution in the brain ofmice
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Arezoo Gohari Mahmoudabad , Fatemeh Gheybi, Mohsen Mehrabi* , Alireza Masoudi, Zeinab Mobasher, Hamid Vahedi, Anneh Mohammad Gharravi, Fatemeh Sadat Bitaraf, Seyed Mahdi Rezayat Sorkhabadi
Phytosome silymarin nanoparticles effectively improved ethanol-induced liver damage in models of rats with alcoholic liver disease (ALD) and showed higher beneficial effects and less toxicity compared to the bulky form of phytosome silymarin nanoparticles.
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Nahid Moradi , Saeid Kaviani* , Mina Soufizomorrod* , Simzar Hosseinzadeh* , Masoud Soleimani
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Mina Yousefnezhad, Soodabeh Davaran* , Mirzaagha Babazadeh, Abolfazl Akbarzadeh, Hamidreza Pazoki-Toroudi
Drug repurposing is an effective strategy for identifying and using approved drugs for new therapeutic purposes. We investigated co-delivery of the antitumor drugs, doxorubicin (DOX), and ezetimibe (EZ) as a cholesterol uptake-blocking drug with PCEC on prostate cancer cell line (PC3).
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Mitra Torabi , Ayuob Aghanejad*, Pouria Savadi , Abolfazl Barzegari, Yadollah Omidi , Jaleh Barar*
Owing to their unique advantages, mesoporous silica nanoparticles (MSNPs) have attracted much attention for drug delivery and targeting. In the current study, MSNPs were fabricated, PEGylated, loaded with sunitinib, and conjugated with mucin-16 aptamer to target CA125 on ovarian cancer cells.
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Nahid Moradi , Mina Soufi-Zomorrod* , Simzar Hosseinzadeh, Masoud Soleimani
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Azadeh Vaezi Moghaddam , Seyed Alireza Mortazavi* , Farzad Kobarfard, Reza Bafkary, Behzad Darbasizadeh
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Seyedeh-Sara Hashemi* , Mohsen Pirmoradi, Alireza Rafati, Mehdi Kian, Ali Akbar Mohammadi* , Mohamad Ali Hoghoughi*
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Samaneh Rashtbari , Zahra Hassanpour Aydinlou , Leila Sadeghi*
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Navid Mosallaei , Amirhossein Malaekeh-Nikouei , Setayesh Sarraf Shirazi, Javad Behmadi, Bizhan Malaekeh-Nikouei*
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Nahid Rezazadeh , Effat Alizadeh, Somaieh Soltani, Soodabeh Davaran* , Neda Esfandiari*
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Azin Shahmohammadi , Hadi Samadian, Saeed Heidari Keshel, Khodabakhsh Rashidi, Amir Kiani, Masoud Soleimani*, Farjam Goudarzi*
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