Pavankumar Kothamasu*, Hemanth Kanumur, Niranjan Ravur, Chiranjeevi Maddu, Radhika Parasuramrajam, Sivakumar Thangavel
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Ailar Nakhlband, Jaleh Barar*
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Hassan Namazi*, Sanaz Motamedi, Mina Namvari
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Ali Nokhodchi*, Shaista Raja, Pryia Patel, Kofi Asare-Addo
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Savitri Shrestha, Sundara Rajan Subaramaihha, Sujan Ganapathy Pasura Subbaiah, Ravi Shankara Birur Eshwarappa*, Dhananjaya Bhadrapura Lakkappa*
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Amna Parveen, Muhammad Sajid Hamid Akash*, Kanwal Rehman, Qaisar Mehmood, Muhammad Imran Qadir*
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Ravi Shankara Birur Eshwarappa, Raman Shanthi Iyer, Sundara Rajan Subbaramaiah, S Austin Richard, Bhadrapura Lakkappa Dhananjaya*
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Hassan Namazi*, Yousef Toomari, Hassan Abbaspour
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Samira Jafari, Solmaz Maleki Dizaj, Khosro Adibkia*
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Reza Heidari, Maryam Rasti, Babak Shirazi Yeganeh, Hossein Niknahad*, Arastoo Saeedi, Asma Najibi
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Jaleh Barar*
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Sonu Gandhi*, Pankaj Suman, Ashok Kumar, Prince Sharma, Neena Capalash, C. Raman Suri
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Azin Jahangiri, Khosro Adibkia*
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Reza Safdari, Reza Ferdousi, Kamal Aziziheris, Sharareh R. Niakan-Kalhori, Yadollah Omidi*
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Marzieh Fathi, Jaleh Barar , Ayuob Aghanejad, Yadollah Omidi*
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Gerard Marshall Raj*, Jayanthi Mathaiyan*, Mukta Wyawahare, Katiboina Srinivasa Rao, Rekha Priyadarshini
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Somayeh Vandghanooni, Morteza Eskandani*
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Behzad Jafari, Farzaneh Rafie, Soodabeh Davaran*
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Yadollah Omidi* , Jaleh Barar
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Jaleh Barar , Ayuob Aghanejad, Marziyeh Fathi, Yadollah Omidi*
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Marziyeh Fathi, Jaleh Barar*
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Jaleh Barar , Mohammad A. Rafi, Mohammad M. Pourseif, Yadollah Omidi*
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Hassan Namazi*, Elnaz Abdollahzadeh
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Marziyeh Fathi, Parham Sahandi Zangabad, Sima Majidi, Jaleh Barar, Hamid Erfan-Niya, Yadollah Omidi*
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Shahram Emami, Mohammadreza Siahi-Shadbad, Khosro Adibkia , Mohammad Barzegar-Jalali*
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Karim Osouli-Bostanabad, Khosro Adibkia*
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Ailar Nakhlband, Morteza Eskandani, Yadollah Omidi , Nazli Saeedi, Samad Ghafari, Jaleh Barar* , Alireza Garjani*
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Ayuob Aghanejad, Hiwa Babamiri, Khosro Adibkia, Jaleh Barar , Yadollah Omidi*
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Prayasee Baruah, Mostofa Ataur Rohman, Semen O. Yesylevskyy, Sivaprasad Mitra*
Two chromone derivatives, CyC and AMC exhibit strong non-competitive acetylcholinesterase (AChE) inhibition. CyC, due to planarity and greater stacking interactions with Peripheral Anionic Site, is the stronger AChE antagonist and plasma protein binder.
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Somayeh Vandghanooni, Morteza Eskandani, Jaleh Barar , Yadollah Omidi*
Aptamers (Aps) are short single-strand nucleic acids, which can be used as the therapeutic and targeting agent in advanced drug delivery systems. Conjugation of Aps with other entities (siRNA, toxins, drugs, DNAzyme/Ribozymes) provides advanced multifunctional nanosystems for cancer therapy.
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Reza Ferdousi , Ali Akbar Jamali , Reza Safdari*
The Market Basket Analysis (MBA) was used to identify bio-elements involved in the occurrence of drug-drug interactions (DDIs), which resulted in the identification of over 200,000 potential DDIs. The MBA can be used in the prediction of nonlinear biological issues.
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Marziyeh Fathi , Azam Safary , Jaleh Barar*
Jaleh Barar (PharmD, PhD) is Professor of Drug Delivery and Targeting. She currently is the chair of the department of Pharmaceutics at the Faculty of Pharmacy, Tabriz university of Medical Sciences. Professor Barar’s research is focused on various aspects of the pharmaceutical cell biology with the particular emphasis on the development of novel drug delivery and targeting strategies to combat cancer.
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Letter to the Editor
COVID-19
Yosef Masoudi-Sobhanzadeh*
This letter aims to introduce drug repurposing methods and the existing challenges to detect candidate drugs which may be helpful in controlling COVID-19.
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Amir Shakouri , Houman Kahroba, Hamed Hamishekar, Jalal Abdolalizadeh*
In the first stage of the procedure, medical leech saliva was extracted and for encapsulating these proteins, liposome technique was applied. Continually, nano drug applied on cancer cells and expression of genes were evaluated by Real- Time PCR and western blotting.
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Samira Gholizadeh , Hossein Haghaei, Hosna Karami, Somaieh Soltani* , Mostafa Zakariazadeh, Javad Shokri
Interaction of the Fingolimod with HSA was studied using multi-spectroscopic and molecular modeling methods. Fingolimod binds to the binding site II of HSA via hydrogen bonds and Van der Walls forces. The binding is enthalpy driven. Fingolimod interaction with HSA leads to the conformational change of HSA.
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Yosef Masoudi-Sobhanzadeh* , Hosein Esmaeili , Ali Masoudi-Nejad*
The required data, including proteins and enzymes, are divided into smaller parts and are mined using the existing processors. The proposed method computes the alignment similarity between the existing proteins and SARS-CoV-2’s proteins based on the proposed fuzzy logic system.
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Muhammad H. Sultan , Wael A. Mahdi, Young M. Kwon*
Pluronic F127 limits tissue enzymes to act on protamine on NPH insulin microcrystals to prevent acceleration of insulin release and help control blood glucose in STZ-induced diabetic rats uponsubcutaneous administration.
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Wael A. Mahdi , Mohammad S. Absar, Suna Choi, Victor C. Yang, Young M. Kwon*
The tPA was successfully modified via enzymatic oxidation by GO, resulting in enhanced control of its activity in the prodrug construct. This approach can be applied to other therapeutic glycoproteins.
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Yadollah Omidi* , Hossein Omidian
Transformation of the academic pharmaceutical and biomedical research centers towards innovative R & D hubs is a dynamic nested complex matter, which can be accomplished via a partnership with pharmaceutical and biomedical manufacturers as well as established and emerging contract research organizations.
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Atena Sharifi-Rad , Zeinab Amiri-Tehranizadeh, Atiye Talebi, Niknaz Nosrati, Morvarid Medalian, Mahtab Pejhan, Nazanin Hamzkanloo, Mohammad Reza Saberi, Parisa Mokaberi, Jamshidkhan Chamani*
The MD simulation and spectroscopic studies of the interaction of ct-DNA and propyl acridone revealed that a transition from the extended nucleic double helix towards the denatured structure.
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Luigi X Cubeddu* , Daisy de la Rosa, Michele Ameruoso
A combination of old age, comorbidities, increased cytokine levels and proarrhythmic drug therapies canexplain the increased arrhythmic events reported in severe COVID-19 disease.
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Fatima Molavi , Mohammad Barzegar-Jalali , Hamed Hamishehkar*
Evaluation of different variables on preparation of Microspheres. F9; Freeze-dried particles prepared by W/O/W emulsion method, F1; Dried particles on the tray at room temperature, F16; Freeze-dried particles prepared by S/O/O emulsion method. W/O/W; Water in oil in water, S/O/O; Solid in oil in oil.
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Aleksandr L. Urakov* , Natalya A. Urakova, Ilnur I. Yagudin, Milena D. Svetova, Darya O. Suntsova
The purpose of this letter was to present a model for evaluating the biological activity of drugs, which can become a new vector for the development of effective ways to increase blood oxygenation across pulmonary and save the lives of patients with severe atypical pneumonia complicated by respiratory obstruction in COVID-19.
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Jurica Novak* , Alena R. Zykova , Vladimir A. Potemkin , Vladimir V. Sharutin, Olga K. Sharutina
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Mitra Torabi , Ayuob Aghanejad*, Pouria Savadi , Abolfazl Barzegari, Yadollah Omidi , Jaleh Barar*
Owing to their unique advantages, mesoporous silica nanoparticles (MSNPs) have attracted much attention for drug delivery and targeting. In the current study, MSNPs were fabricated, PEGylated, loaded with sunitinib, and conjugated with mucin-16 aptamer to target CA125 on ovarian cancer cells.
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Navid Mohammadjani , Sahand Karimi, Musa Moetasam Zorab , Morahem Ashengroph* , Mehran Alavi*
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Sara Shamsian , Babak Sokouti, Siavoush Dastmalchi*
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Navid Mosallaei , Amirhossein Malaekeh-Nikouei , Setayesh Sarraf Shirazi, Javad Behmadi, Bizhan Malaekeh-Nikouei*
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Saman Heydari , Mohammad Barzegar-Jalali, Mostafa Heydari, Afsaneh Radmehr, Ana Cláudia Paiva-Santos, Maryam Kouhsoltani, Hamed Hamishehkar*
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